Cyclic AC253
Product Sizes
1 mg
£ POA
HY-P10235-1MG
10 mg
£ POA
HY-P10235-10MG
5 mg
£ POA
HY-P10235-5MG
About this Product
- SKU:
- HY-P10235
- Extra Details:
- Cyclic AC253 is an antagonist for amylin receptor; with IC50 of 0.3 μM. Cyclic AC253 exhibits neuroprotective efficacy against Aβ toxicity and abrogates Aβ-induced impairment of hippocampal long-term potentiation. Cyclic AC253 penetrate blood-brain barrier (BBB)[1].
- Molecular Weight:
- 3009.34
- Purity:
- 99.83
- References:
- [1]Soudy R, et al., Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's disease. Alzheimers Dement (N Y). 2016 Dec 10;3(1):44-56.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein
