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Proteins and Peptides

Cyclo(CRLLIF)

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HY-P10222-1EACH
About this Product
SKU:
HY-P10222
Application:
Antibody Microarray
Extra Details:
Cyclo CRLLIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2; which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β; with affinity for HIF1-α and HIF2-α PAS-B domains KD of 14.5 and 10.2 μM; respectively[1].
Molecular Weight:
745.98
References:
[1]Ball AT, et al., Identification and Development of Cyclic Peptide Inhibitors of Hypoxia Inducible Factors 1 and 2 That Disrupt Hypoxia-Response Signaling in Cancer Cells. J Am Chem Soc. 2024 Mar 19.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
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