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Proteins and Peptides

Ac-DEVD-AMC

Product Sizes
5 mg
£ POA
HY-P1003-5MG
1 mg
£ POA
HY-P1003-1MG
10 mg
£ POA
HY-P1003-10MG
25 mg
£ POA
HY-P1003-25MG
50 mg
£ POA
HY-P1003-50MG
100 mg
£ POA
HY-P1003-100MG
About this Product
SKU:
HY-P1003
Application:
Antibody Microarray
CAS Number:
169332-61-0
Extra Details:
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate; Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection; with an excitation wavelength of 380 nm and an emission wavelength of 460 nm[1][2][3].
Molecular Weight:
675.64
Purity:
99.93
References:
[1]Nobel CS, et al. Disulfiram is a potent inhibitor of proteases of the caspase family. Chem Res Toxicol. 1997 Dec;10(12):1319-24. |[2]Ochu EE, et al. Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells. J Neurochem. 1998 Jun;70(6):2637-40. |[3]Yakovlev AA, Gorokhovatsky AY, Onufriev MV, Beletsky IP, Gulyaeva NV. Brain cathepsin B cleaves a caspase substrate. Biochemistry (Mosc). 2008 Mar;73(3):332-6.
Research Area:
Others
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
Pathway:
Others
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