Taspoglutide
Product Sizes
5 mg
£ POA
HY-P0165-5MG
10 mg
£ POA
HY-P0165-10MG
1 mg
£ POA
HY-P0165-1MG
25 mg
£ POA
HY-P0165-25MG
About this Product
- SKU:
- HY-P0165
- Additional Names:
- ITM077; R1583; BIM51077
- Application:
- Immunoprecipitation
- CAS Number:
- 275371-94-3
- Extra Details:
- Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes; with an EC50 value of 0.06 nM.
- Molecular Weight:
- 3339.71
- Purity:
- 99.51
- References:
- [1]Sebokova E, et al. Taspoglutide, an analog of human glucagon-like Peptide-1 with enhanced stability and in vivo potency. Endocrinology. 2010 Jun;151(6):2474-82.|[2]Retterstol K, et al. Taspoglutide: a long acting human glucagon-like polypeptide-1 analogue. Expert Opin Investig Drugs. 2009 Sep;18(9):1405-11.|[3]Nauck MA, et al. Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combination with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: a double-blind placebo-controlled study. Diabetes Care. 2009 Jul;32(7):1237-43.|[4]Sebokova E, et al. Taspoglutide, a novel human once-weekly analogue of glucagon-like peptide-1, improves glucose homeostasis and body weight in the Zucker diabetic fatty rat. Diabetes Obes Metab. 2010 Aug;12(8):674-82.|[5]Panjwani N, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology. 2013 Jan;154(1):127-39.|[6]Panjwani N, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology. 2013 Jan;154(1):127-39.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein
