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Proteins and Peptides

Gap 27

Product Sizes
50 mg
£ POA
HY-P0139-50MG
1 mg
£ POA
HY-P0139-1MG
25 mg
£ POA
HY-P0139-25MG
10 mg
£ POA
HY-P0139-10MG
5 mg
£ POA
HY-P0139-5MG
About this Product
SKU:
HY-P0139
CAS Number:
198284-64-9
Extra Details:
Gap 27; a synthetic connexin43 mimetic peptide; is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment[1][2].
Molecular Weight:
1304.53
Purity:
99.90
References:
[1]Ilvesaro J, et al. Connexin-mimetic peptide Gap 27 decreases osteoclastic activity. BMC Musculoskelet Disord. 2001;2:10.|[2]Edwards G, et al. Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol. 1999 Dec;128(8):1788-94.|[3]Chaytor AT,e t al. Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol. 1998 Apr 15;508 ( Pt 2):561-73.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
Cytoskeleton
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