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Proteins and Peptides

D-JNKI-1

Product Sizes
5 mg
£ POA
HY-P0069-5MG
1 mg
£ POA
HY-P0069-1MG
10 mg
£ POA
HY-P0069-10MG
About this Product
SKU:
HY-P0069
Additional Names:
AM-111; XG-102
CAS Number:
1445179-97-4
Extra Details:
D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK.
Molecular Weight:
3822.44
Purity:
99.29
References:
[1]Wang J, et al. A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss. J Neurosci. 2003 Sep 17;23(24):8596-607.|[2]Zhao Y, et al. The JNK inhibitor D-JNKI-1 blocks apoptotic JNK signaling in brain mitochondria. Mol Cell Neurosci. 2012 Mar;49(3):300-10.|[3]Kersting S, et al. The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium. J Inflamm Res. 2013 May 3;6:71-81.|[4]Wang C, et al. Wu-tou decoction attenuates neuropathic pain via suppressing spinal astrocytic IL-1R1/TRAF6/JNK signaling. Oncotarget. 2017 Oct 6;8(54):92864-92879.
Research Area:
Others
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
MAPK/ERK Pathway
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