Cyclo(-RGDfK) (TFA)
Product Sizes
10 mg
£ POA
HY-P0023A-10MG
50 mg
£ POA
HY-P0023A-50MG
5 mg
£ POA
HY-P0023A-5MG
25 mg
£ POA
HY-P0023A-25MG
100 mg
£ POA
HY-P0023A-100MG
About this Product
- SKU:
- HY-P0023A
- CAS Number:
- 500577-51-5
- Extra Details:
- Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin; with an IC50 of 0.94 nM[1]. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[3].
- Molecular Weight:
- 717.69
- Purity:
- 99.61
- References:
- [1]Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95.|[2]Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- Cytoskeleton
