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Proteins and Peptides

Cyclo(-RGDfK)

Product Sizes
100 mg
£ POA
HY-P0023-100MG
50 mg
£ POA
HY-P0023-50MG
1 mg
£ POA
HY-P0023-1MG
5 mg
£ POA
HY-P0023-5MG
25 mg
£ POA
HY-P0023-25MG
10 mg
£ POA
HY-P0023-10MG
About this Product
SKU:
HY-P0023
Application:
Antibody Microarray
CAS Number:
161552-03-0
Extra Details:
Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin; with an IC50 of 0.94 nM. Cyclo(-RGDfK) potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[1][2].
Molecular Weight:
603.67
Purity:
99.83
References:
[1]Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95.|[2]Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
Cytoskeleton
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