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Proteins and Peptides

2-Amino-2-deoxyglucose (hydrochloride)

Product Sizes
100 mg
£ POA
HY-N9459-100MG
250 mg
£ POA
HY-N9459-250MG
500 mg
£ POA
HY-N9459-500MG
1 g
£ POA
HY-N9459-1G
10mM/1mL
£ POA
HY-N9459-10MM
About this Product
SKU:
HY-N9459
Additional Names:
D-Glucosamine Hydrochloride
CAS Number:
1078691-95-8
Extra Details:
2-Amino-2-deoxyglucose hydrochloride (D-Glucosamine Hydrochloride) is a glucose analog that is specifically recognized and transported by the cell membrane GLUT1. 2-Amino-2-deoxyglucose hydrochloride acts as a tumor-targeting ligand and a guiding molecule for the synthesis of prodrug conjugates; thus delivering drugs precisely to tumor cells. 2-Amino-2-deoxyglucose hydrochloride is applicable to diagnostic imaging and therapeutic efficacy monitoring of solid tumors and various cancers (e.g.; breast cancer; glioblastoma). 2-Amino-2-deoxyglucose hydrochloride also helps bacteria resist lysozyme digestion by integrating into the non-N-acetylated residues of Streptococcus pneumoniae peptidoglycan. 2-Amino-2-deoxyglucose hydrochloride is used in studies on tumor metabolism and the exploration of bacterial drug resistance mechanisms[1][2].
Molecular Weight:
215.63
Purity:
98.0
References:
[1]Späte AK, et al. Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels-Alder reactions. Beilstein J Org Chem. 2014;10:2235-2242. Published 2014 Sep 22.
Research Area:
Cancer;Infection;Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Others
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