(+)-Medioresinol
Product Sizes
1 mg
£ POA
HY-N3307-1MG
5 mg
£ POA
HY-N3307-5MG
10 mg
£ POA
HY-N3307-10MG
About this Product
- SKU:
- HY-N3307
- CAS Number:
- 40957-99-1
- Extra Details:
- (+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection; inflammation; and ischemic stroke[1][2][3][4][5].
- Molecular Weight:
- 388.41
- Purity:
- 99.13
- References:
- [1] Ji Hong Hwang, et al. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. Biochimie. 2012 Aug;94(8):1784-93.|[2]Ji Hong Hwang, et al. Synergistic antibacterial and antibiofilm effect between (+)-medioresinol and antibiotics in vitro. Appl Biochem Biotechnol. 2013 Aug;170(8):1934-41.
- Research Area:
- Infection; Inflammation/Immunology; Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
