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Proteins and Peptides

Bisandrographolide A

Product Sizes
1 mg
£ POA
HY-N2940-1MG
5 mg
£ POA
HY-N2940-5MG
About this Product
SKU:
HY-N2940
Additional Names:
BAA
CAS Number:
160498-00-0
Extra Details:
Bisandrographolide A (BAA) activates TRPV4 channel with an EC50 of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory; immunostimulant; and antihypertensive compound[1][2].
Molecular Weight:
664.87
References:
[1]Yue GG, et al. Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo. Phytomedicine. 2022 Jul 20;102:154183.|[2]Vriens J, et al. Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. J Biol Chem. 2007 Apr 27;282(17):12796-803.
Research Area:
Inflammation/Immunology; Cardiovascular Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Membrane Transporter/Ion Channel;Neuronal Signaling
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