(E)-Methyl 4-coumarate
Product Sizes
1 g
£ POA
HY-N2492-1G
100 g
£ POA
HY-N2492-100G
50 g
£ POA
HY-N2492-50G
5 g
£ POA
HY-N2492-5G
25 g
£ POA
HY-N2492-25G
10 g
£ POA
HY-N2492-10G
10mM/1mL
£ POA
HY-N2492-10MM
About this Product
- SKU:
- HY-N2492
- Additional Names:
- Methyl trans-p-coumarate
- CAS Number:
- 19367-38-5
- Extra Details:
- (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate) is a phenolic compound and derivative of Cinnamic acid (HY-N0610A). (E)-Methyl 4-coumarate can be found in several plants; such as the leaves of Allium cepa and Morinda citrifolia L. (E)-Methyl 4-coumarate; when combined with Carnosic acid (HY-N0644); induces Apoptosis. (E)-Methyl 4-coumarate inhibits GSK3β activity and modulates inflammatory cytokine levels (increasing IL-10 and decreasing IL-4). (E)-Methyl 4-coumarate combined with Carnosic acid exhibits anticancer effects against acute myeloid leukemia. (E)-Methyl 4-coumarate ameliorates Plasmodium berghei NK65 infection[1][2].
- Molecular Weight:
- 178.19
- Purity:
- 99.87
- References:
- [1]Trachtenberg A, et al. Synergistic Cytotoxicity of Methyl 4-Hydroxycinnamate and Carnosic Acid to Acute Myeloid Leukemia Cells via Calcium-Dependent Apoptosis Induction. Front Pharmacol. 2019 May 9;10:507.
- Research Area:
- Cancer; Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis
