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Proteins and Peptides

11beta-Hydroxyprogesterone

Product Sizes
100 mg
£ POA
HY-N2337-100MG
25 mg
£ POA
HY-N2337-25MG
50 mg
£ POA
HY-N2337-50MG
10 mg
£ POA
HY-N2337-10MG
5 mg
£ POA
HY-N2337-5MG
10mM/1mL
£ POA
HY-N2337-10MM
About this Product
SKU:
HY-N2337
Additional Names:
11β-Hydroxyprogesterone
CAS Number:
600-57-7
Extra Details:
11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED50 of 10 nM.
Molecular Weight:
330.47
Purity:
99.61
References:
[1]Rafestin-Oblin ME, et al. 11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells. Mol Pharmacol. 2002 Dec;62(6):1306-13.|[2]Souness GW, et al. 11 alpha- and 11 beta-hydroxyprogesterone, potent inhibitors of 11 beta-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat. Hypertension. 1996 Mar;27(3 Pt 1):421-5.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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