1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)
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HY-N1743-1EACH
About this Product
- SKU:
- HY-N1743
- Application:
- Immunoprecipitation
- CAS Number:
- 376362-03-7
- Extra Details:
- 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl); isolated from Broussonetia kazinoki; shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes[1].
- Molecular Weight:
- 326.43
- References:
- [1]Jing-Jing Xue, et al. Flavans and diphenylpropanes with PTP1B inhibition from <i>Broussonetia kazinoki</i>. Fitoterapia. 2018 Oct;130:37-42.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
