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Proteins and Peptides

10S;13aR-Antofine N-oxide

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HY-N17304-1EACH
About this Product
SKU:
HY-N17304
Application:
Antibody Microarray
CAS Number:
314744-17-7
Extra Details:
10S;13aR-Antofine N-oxide is a phenanthroindolizidine N-oxide alkaloid and cytotoxic agent found in Cynanchum vincetoxicum. 10S;13aR-Antofine N-oxide exerts cytotoxic effects in drug-sensitive (KB-3-1; IC50 = 0.11 μM) and multi-drug-resistant (KB-V1; IC50 = 0.16 μM) carcinoma cells. 10S; 13aR-Antofine N-oxide acts as a poor substrate for the P-glycoprotein (P-170) efflux pump. 10S;13aR-Antofine N-oxide can be used for the research of cancers[1].
Molecular Weight:
379.45
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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