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Proteins and Peptides

(rel)-Salcolin A

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HY-N16764-1EACH
About this Product
SKU:
HY-N16764
Application:
Electron Microscopy
CAS Number:
1977557-69-9
Extra Details:
(rel)-Salcolin A is a flavonoid lignan compound with anticancer; anti-inflammatory; and neuroprotective activities. (rel)-Salcolin A has IC50 values ??of 66.69 μM and 56.12 μM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1); respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC50 of 14.65 μM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells; inhibiting the production of the inflammatory factor NO; and protecting against glutamate-induced neuronal cell damage; with a neuroprotective E50 of 47.44 μM. (rel)-Salcolin A can be used in research related to thyroid cancer; anti-inflammation; and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn)[1][2].
Molecular Weight:
526.49
Research Area:
Cancer;Endocrinology;Inflammation/Immunology;Neurological Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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