(R)-(+)-O-Demethylbuchenavianine
Product Sizes
1 mg
£ POA
HY-N12625-1MG
About this Product
- SKU:
- HY-N12625
- CAS Number:
- 1364123-68-1
- Extra Details:
- (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1; CDK5; glycogen synthase kinase-3 (GSK3); cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A); with IC50s of 1.1; 0.95; >10; >10 and >10 μM; respectively[1].
- Molecular Weight:
- 351.40
- Purity:
- 98.67
- References:
- [1]Nguyen TB, et al., Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. J Med Chem. 2012 Mar 22;55(6):2811-9.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
