6,6′-Dihydroxythiobinupharidine
Product Sizes
6,6′-Dihydroxythiobinupharidine
£ POA
HY-N12129
About this Product
- SKU:
- HY-N12129
- CAS Number:
- 30343-70-5
- Extra Details:
- 6,6′-Dihydroxythiobinupharidine is a cysteine proteases inhibitor. 6,6′-Dihydroxythiobinupharidine can enhance DNA cleavage mediated by human topoisomerase IIα and IIβ ~8-fold and ~3-fold, respectively[1][2].
- Molecular Weight:
- 526.73
- References:
- [1]Yamahara J, et al. Potent immunosuppressive principles, dimeric sesquiterpene thioalkaloids, isolated from nupharis rhizoma, the rhizoma of Nuphar pumilum (nymphaeaceae): structure-requirement of nuphar-alkaloid for immunosuppressive activity. Biol Pharm Bull. 1996;19(9):1241-1243.|[2]Dalvie ED, et al. 6,6'-Dihydroxythiobinupharidine as a poison of human type II topoisomerases. Bioorg Med Chem Lett. 2019;29(15):1881-1885.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
