FK-3000
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HY-N11097-1EACH
About this Product
- SKU:
- HY-N11097
- CAS Number:
- 1054312-81-0
- Extra Details:
- FK-3000 is a potent anti-tumor agent that inhibits the growth of carcinoma cells through apoptosis and induction cell cycle arrest. FK-3000 also exhibit antiviral effects against HSV-1 and HIV-1[1][2][3][4].
- Molecular Weight:
- 417.45
- References:
- [1]Xu HD, et, al. FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression. Int J Oncol. 2015;46(6):2309-16. |[2]Li YC, et, al. 6,7-di-O-acetylsinococuline (FK-3000) induces G2/M phase arrest in breast carcinomas through p38 MAPK phosphorylation and CDC25B dephosphorylation. Int J Oncol. 2015 Feb;46(2):578-86. |[3]Nawawi A, et, al. In vivo antiviral activity of Stephania cepharantha against herpes simplex virus type-1. Phytother Res. 2001 Sep;15(6):497-500. |[4]Lee JH, et, al. Development of a LC-MS method for quantification of FK-3000 and its application to in vivo pharmacokinetic study in drug development. J Pharm Biomed Anal. 2012 Nov;70:587-91.
- Research Area:
- Cancer; Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
