(±)-Eriodictyol
Product Sizes
5 mg
HY-N0637A-5MG
10 mg
HY-N0637A-10MG
About this Product
- SKU:
- HY-N0637A
- Additional Names:
- (±)-Huazhongilexone; Dihydroluteolin
- Application:
- Electron Microscopy
- CAS Number:
- 4049-38-1
- Extra Details:
- (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM; rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1; VEGF; eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia; enhances the activity and cytotoxicity of immune cells (such as B lymphocytes; NK cells and macrophages); and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy; acute lung injury and various pain-related diseases[1][2][3][4][5].
- Molecular Weight:
- 288.25
- Purity:
- 99.9
- References:
- [1]Souichi Nakashima, et al. Inhibitors of melanogenesis in B16 melanoma 4A5 cells from flower buds of Lawsonia inermis (Henna). Bioorg Med Chem Lett. 2015 Jul 1;25(13):2702-6.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
