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Proteins and Peptides

1-Caffeoylquinic acid

Product Sizes
5 mg
£ POA
HY-N0460-5MG
1 mg
£ POA
HY-N0460-1MG
10 mg
£ POA
HY-N0460-10MG
10mM/1mL
£ POA
HY-N0460-10MM
About this Product
SKU:
HY-N0460
Application:
Antibody Microarray
CAS Number:
1241-87-8
Extra Details:
1-Caffeoylquinic acid is an effective NF-κB inhibitor; shows significant binding affinity to the RH domain of p105 with Ki of 0.007 μM[1]. 1-Caffeoylquinic acid has anti-oxidative stress ability[2]. 1-Caffeoylquinic acid is the Inhibitor for PD-1/PD-L1[3].
Molecular Weight:
354.31
Purity:
99.54
References:
[1]Khan MK, et al. Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105. Pharmacogn Mag. 2013 Jan;9(33):51-7.|[2]Jiang Y, et al. Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model. BMC Complement Altern Med. 2017 Jun 17;17(1):320.|[3]Han Y, et al. PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopy. Anal Biochem. 2018 Apr 15;547:52-56.|[4]Sun Y, et al., Qualitative and quantitative analysis of phenolics in Tetrastigma hemsleyanum and their antioxidant and antiproliferative activities. J Agric Food Chem. 2013 Nov 6;61(44):10507-15.
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Immunology/Inflammation;NF-κB
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