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Proteins and Peptides

(E)-Ethyl p-methoxycinnamate

Product Sizes
25 g
£ POA
HY-N0346A-25G
5 g
£ POA
HY-N0346A-5G
10 g
£ POA
HY-N0346A-10G
10mM/1mL
£ POA
HY-N0346A-10MM
About this Product
SKU:
HY-N0346A
CAS Number:
24393-56-4
Extra Details:
(E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory; anti-neoplastic and anti-microbial effects. (E)-Ethyl p-methoxycinnamate inhibits COX-1 and COX-2 in vitro with IC50s of 1.12 and 0.83 μM; respectively[1].
Molecular Weight:
206.24
Purity:
99.39
References:
[1]Umar MI, et al. Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from <i>Kaempferia galangal</i> L. extracts. Molecules. 2012 Jul 23;17(7):8720-34.|[2]Adisakwattana S, et al., Structure-activity relationships of trans-cinnamic acid derivatives on alpha-glucosidase inhibition. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2893-6.|[3]He ZH, et al., Antiangiogenic effects and mechanisms of trans-ethyl p-methoxycinnamate from Kaempferia galanga L. J Agric Food Chem. 2012 Nov 14;60(45):11309-17.|[4]Umar M I, et al. Cytotoxic and pro-apoptotic properties of Ethyl-P-methoxycinnamate and its hydrophilic derivative potassium-P-methoxycinnamate[J]. Chemistry Africa, 2018, 1: 87-95.
Research Area:
Cancer; Infection; Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease
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