Hyodeoxycholic acid
Product Sizes
500 mg
£ POA
HY-N0169-500MG
100 mg
£ POA
HY-N0169-100MG
10 g
£ POA
HY-N0169-10G
5 g
£ POA
HY-N0169-5G
1 g
£ POA
HY-N0169-1G
10mM/1mL
£ POA
HY-N0169-10MM
About this Product
- SKU:
- HY-N0169
- Additional Names:
- HDCA
- Application:
- Immunoprecipitation
- CAS Number:
- 83-49-8
- Extra Details:
- Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora; and acts as a TGR5 (GPCR19) agonist; with an EC50 of 31.6 µM in CHO cells.
- Molecular Weight:
- 392.57
- Purity:
- 99.89
- References:
- [1]Sato H, et al. Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem. 2008 Mar 27;51(6):1831-41.|[2]Shih DM, et al. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. FASEB J. 2013 Sep;27(9):3805-17.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Metabolic Enzyme/Protease
