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Proteins and Peptides

(Rac)-Salvianic acid A (sodium)

Product Sizes
5 mg
£ POA
HY-N0106-5MG
10 mg
£ POA
HY-N0106-10MG
100 mg
£ POA
HY-N0106-100MG
50 mg
£ POA
HY-N0106-50MG
200 mg
£ POA
HY-N0106-200MG
10mM/1mL
£ POA
HY-N0106-10MM
About this Product
SKU:
HY-N0106
Additional Names:
(Rac)-Danshensu (sodium); (Rac)-Tanshinol (sodium)
Application:
Antibody Microarray
CAS Number:
67920-52-9
Extra Details:
(Rac)-Salvianic acid A sodium is the racemic form of Salvianic acid A (HY-N1913). Salvianic acid A is an orally active phenolic compound that induces Nrf2/HO-1 activation and inhibits the NF-κB pathway; and it also activates the mitochondrial antioxidant defense system (Mitochondrial Metabolism). Salvianic acid A exhibits anti-inflammatory; antioxidant; and anti-apoptotic properties (Apoptosis); demonstrating potential for research into inflammation and cardiovascular diseases[1][2][3][4][5][6][7].
Molecular Weight:
220.15
Purity:
98.0
References:
[1]Wei Wang, et al. Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation. Acta Pharmacol Sin. 2022 Apr;43(4):771-780. |[2]V Bharath Kumar, et al. Sodium Danshensu Inhibits Oral Cancer Cell Migration and Invasion by Modulating p38 Signaling Pathway. Front Endocrinol (Lausanne). 2020 Sep 30:11:568436. |[3]Chen Yu, et al. Danshensu attenuates cisplatin-induced nephrotoxicity through activation of Nrf2 pathway and inhibition of NF-κB. Biomed Pharmacother. 2021 Oct:142:111995. |[4]Wu Y, et al. The Effect of Salvianolic Acid on Vascular Protection and Possible Mechanisms. Oxid Med Cell Longev. 2020 Sep 25;2020:5472096. doi: 10.1155/2020/5472096.|[5]Zhao QT, et al. Salvianic acid A inhibits lipopolysaccharide-induced apoptosis through regulating glutathione peroxidase activity and malondialdehyde level in vascular endothelial cells. Chin J Nat Med. 2012 Jan;10(1):53-7.|[6]Zhao QT, et al. Salvianic acid A inhibits lipopolysaccharide-induced apoptosis through regulating glutathione peroxidase activity and malondialdehyde level in vascular endothelial cells. Chin J Nat Med. 2012 Jan;10(1):53-7.|[7]Jia D, et al. Salvianic acid A sodium protects HUVEC cells against tert-butyl hydroperoxide induced oxidative injury via mitochondria-dependent pathway. Chem Biol Interact. 2018 Jan 5;279:234-242.
Research Area:
Infection; Inflammation/Immunology; Cardiovascular Disease
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Metabolic Enzyme/Protease;NF-κB
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