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Proteins and Peptides

(E;E)-Bisdemethoxycurcumin (Standard)

Product Sizes
100 mg
£ POA
HY-N0007R-100MG
50 mg
£ POA
HY-N0007R-50MG
10 mg
£ POA
HY-N0007R-10MG
5 mg
£ POA
HY-N0007R-5MG
25 mg
£ POA
HY-N0007R-25MG
About this Product
SKU:
HY-N0007R
Additional Names:
(E;E)-Curcumin III (Standard); (E;E)-Didemethoxycurcumin (Standard)
Application:
Antibody Microarray
CAS Number:
33171-05-0
Extra Details:
(E;E)-Bisdemethoxycurcumin (Standard) is the analytical standard of (E;E)-Bisdemethoxycurcumin. This product is intended for research and analytical applications. (E;E)-Bisdemethoxycurcumin ((E;E)-Curcumin III) is a curcumin derivative with anti-inflammatory and anticancer activities[1][2][3][4][5][6].
Molecular Weight:
308.33
Purity:
98.53
References:
[1]Lee PJ, et al. Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2. Molecules. 2015 Jan 14;20(1):1277-92.|[2]Chen J, et al. Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells. Food Funct. 2014 Dec 24.|[3]Luo C, et al. Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction. Oncol Lett. 2015 Jan;9(1):270-274.|[4]Li YB, et al. Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. Evid Based Complement Alternat Med. 2013;2013:851714.|[5]Yodkeeree S, et al. Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA. J Nutr Biochem. 2009 Feb;20(2):87-95.|[6]Lai CS, et al. Bisdemethoxycurcumin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Obesity in High-Fat Diet-Fed C57BL/6 Mice. J Agric Food Chem. 2016 Feb 3;64(4):821-30.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; sealed storage; away from light and moisture
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Autophagy
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