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Proteins and Peptides

(Rac)-Apremilast

Product Sizes
5 mg
£ POA
HY-I0635-5MG
50 mg
£ POA
HY-I0635-50MG
25 mg
£ POA
HY-I0635-25MG
10 mg
£ POA
HY-I0635-10MG
100 mg
£ POA
HY-I0635-100MG
10mM/1mL
£ POA
HY-I0635-10MM
About this Product
SKU:
HY-I0635
Additional Names:
(Rac)-CC-10004
CAS Number:
253168-86-4
Extra Details:
(Rac)-Apremilast ((Rac)-CC-10004) is the racemic mixture of Apremilast. (Rac)-Apremilast has anti-inflammatory properties and can be used for research on inflammatory diseases; such as psoriasis[1][2].
Molecular Weight:
460.50
Purity:
99.53
References:
[1]Armstrong AW, et al. Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial. J Am Acad Dermatol. 2023 Jan;88(1):29-39. |[2]Man H W, et al. Discovery of (S)-N-{2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1, 3-dioxo-2, 3-dihydro-1 H-isoindol-4-yl} acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-α inhibitor[J]. Journal of medicinal chemistry, 2009, 52(6): 1522-1524.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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