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Proteins and Peptides

Fosribnicotinamide

Product Sizes
10 mg
£ POA
HY-F0004-10MG
5 mg
£ POA
HY-F0004-5MG
100 mg
£ POA
HY-F0004-100MG
50 mg
£ POA
HY-F0004-50MG
10mM/1mL
£ POA
HY-F0004-10MM
About this Product
SKU:
HY-F0004
Additional Names:
β-Nicotinamide mononucleotide; β-NM; NMN
CAS Number:
1094-61-7
Extra Details:
Fosribnicotinamide (β-nicotinamide mononucleotide) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions; cardioprotection; diabetes; Alzheimer's disease; and complications associated with obesity[1].
Molecular Weight:
334.22
Purity:
99.94
References:
[1]Poddar SK, et al. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule. Biomolecules. 2019;9(1):34. Published 2019 Jan 21.|[2]Lv H, et al. NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion [published online ahead of print, 2020 Nov 3]. Cell Metab. 2020;S1550-4131(20)30554-4.|[3]Li J, et al. p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities. Proc Natl Acad Sci U S A. 2019;116(39):19626-19634.|[4]Yoshino J, et al Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536.
Research Area:
Cancer; Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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