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Molecular Biology

NADP (sodium salt)

Product Sizes
100 mg
HY-F0002-100MG
500 mg
HY-F0002-500MG
10mM/1mL
HY-F0002-10MM
About this Product
SKU:
HY-F0002
Additional Names:
Sodium NADP
CAS Number:
1184-16-3
Extra Details:
NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism; which is alternately oxidized (NADP+) and reduced (NADPH); and can maintain cellular redox homeostasis and regulate many biological events; including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation; redox homeostasis; and synthetic metabolism processes[1][4].
Molecular Weight:
765.39
Purity:
99.04
References:
[1]Chen L, et al. NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. Nat Metab. 2019 Mar;1:404-415. Epub 2019 Mar 11. PMID: 31058257; PMCID: PMC6489125.|[2]Nam TS, et al. Interleukin-8 drives CD38 to form NAADP from NADP+ and NAAD in the endolysosomes to mobilize Ca2+ and effect cell migration. FASEB J. 2020 Sep;34(9):12565-12576. |[3]Ilter D, et al. NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis. Redox Biol. 2023 May;61:102627. |[4]Lee SH, et al. Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress. Mol Cells. 2010 Feb 28;29(2):203-8.
Research Area:
Cancer; Metabolic Disease; Inflammation/Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; sealed storage; away from moisture)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Metabolic Enzyme/Protease
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