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Proteins and Peptides

EGFR G719S Recombinant Human Active Protein Kinase

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HY-E70705-1EACH
About this Product
SKU:
HY-E70705
Extra Details:
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited; dimerization-incompetent; state at the plasma membrane (PM). Ligand binding promotes receptor dimerization; which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR G719S Recombinant Human Active Protein Kinase is a recombinant EGFR G719S protein that can be used to study EGFR G719S-related functions[1].
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
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