EGFR d746-750/T790M/C797S/L858R Recombinant Human Active Protein Kinase
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HY-E70700-1EACH
About this Product
- SKU:
- HY-E70700
- Extra Details:
- EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited; dimerization-incompetent; state at the plasma membrane (PM). Ligand binding promotes receptor dimerization; which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR d746-750/T790M/C797S/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR d746-750/T790M/C797S/L858R protein that can be used to study EGFR d746-750/T790M/C797S/L858R-related functions[1].
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
