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Proteins and Peptides

O-Glycoprotease

Product Sizes
2 KU
£ POA
HY-E70565-2KU
About this Product
SKU:
HY-E70565
Extra Details:
O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila; recombinantly expressed in E.coli; with a 6×His tag at the C-terminus. The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl; but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn2+.
References:
[1]Riley NM, et al. Deciphering O-glycoprotease substrate preferences with O-Pair Search. Mol Omics. 2022 Dec 5;18(10):908-922.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
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