Mucinase StcE
Product Sizes
100 μg
£ POA
HY-E70562-100UG
About this Product
- SKU:
- HY-E70562
- Extra Details:
- Mucinase StcE is a zinc metalloproteinase belonging to the M66 family; which is secreted by enterohemorrhagic Escherichia coli via the type II general secretion pathway. Mucinase StcE specifically recognizes and cleaves the 'T*XT' motif in mucin-type glycoproteins with α-O-glycans (such as MUC2; Mucin 7; Glycoprotein 340; CD45; CD43; C1 Esterase Inhibitor (HY-P991629); etc.). By degrading the mucus layer to reduce its viscosity; inhibiting complement cascade activation; and localizing complement regulatory factors to the cell membrane; Mucinase StcE helps bacteria penetrate the mucosal barrier; adhere to host cells; and evade immune clearance. Mucinase StcE can serve as a mucin-specific proteolytic tool for research on mucinous carcinomas derived from the colon; esophagus; and salivary glands[1][2].
- Purity:
- 0
- Research Area:
- Cancer;Infection
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
