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Proteins and Peptides

NAD Synthetase

Product Sizes
5 KU
£ POA
HY-E70410-5KU
10 KU
£ POA
HY-E70410-10KU
About this Product
SKU:
HY-E70410
Additional Names:
NAD+ Synthetase; Nicotinamide adenine dinucleotide synthetase
CAS Number:
9032-69-3
Extra Details:
NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD). The Km values for NAD; ATP; and ammonia of NAD synthetase from Escherichia coli are 200 μM; 11 μM; and 0.65 μM; respectively; while the Km values for NAD; ATP; and ammonia of NAD synthetase from yeast are 170 μM; 190 μM; and 64 μM; respectively. NAD synthetase can be used for enzymatic assays to determine ATP; ammonia; urea; or creatinine; and is also suitable for enzymatic cycling methods. Additionally; NAD synthetase holds potential for research into metabolic diseases; cancer; aging; and neurodegenerative diseases[1][2].
References:
[1]Zalkin H. NAD synthetase. Methods Enzymol. 1985;113:297-302.|[2]Xie N, et al. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Signal Transduct Target Ther. 2020 Oct 7;5(1):227.
Research Area:
Cancer; Metabolic Disease; Neurological Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
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