N-Acetylgalactosaminyltransferase 1
Product Sizes
20 μg
£ POA
HY-E70290-20UG
About this Product
- SKU:
- HY-E70290
- Additional Names:
- GALNT1
- Application:
- Antibody Microarray
- Extra Details:
- N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer can promote abnormal O-glycosylation of CD44; thereby activating the Wnt/β-catenin signaling pathway and regulating the malignant behavior of gastric cancer cells. Additionally; N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying the O-glycosylation of various glycoproteins; such as mucin (MUC1); osteopontin (OPN); matrix metalloproteinase-14 (MMP14); and integrin α3[1].
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
