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Proteins and Peptides

Collagenase; Type VIII

Product Sizes
100 mg
£ POA
HY-E70005H-100MG
10 mg
£ POA
HY-E70005H-10MG
50 mg
£ POA
HY-E70005H-50MG
25 mg
£ POA
HY-E70005H-25MG
5 mg
£ POA
HY-E70005H-5MG
About this Product
SKU:
HY-E70005H
CAS Number:
9001-12-1
Extra Details:
Collagenase; Type VIII is a mixed enzyme derived from Clostridium histolyticum that contains collagenase; a nonspecific protease; and a clostripain. Collagenase; Type VIII can hydrolyze Type VIII collagen and may be used to study the formation of atherosclerosis. Type VIII collagen is a regulator of endothelial cell differentiation and angiogenesis; a substrate for cell adhesion and migration such as smooth muscle cells; and may accumulate in atherosclerosis. After endotoxin activates the expression of Collagenase; Type VIII; it can reduce the production of Type VIII collagen and has the potential to inhibit atherosclerosis[1].
Molecular Weight:
N/A
Purity:
0
References:
[1]Plenz GA, et al. Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis. Atherosclerosis. 2003 Jan;166(1):1-11.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Pathway:
Metabolic Enzyme/Protease
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