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Proteins and Peptides

DQ-BSA-RED

Product Sizes
1 mg
£ POA
HY-D2449-1MG
10 mg
£ POA
HY-D2449-10MG
5 mg
£ POA
HY-D2449-5MG
About this Product
SKU:
HY-D2449
Extra Details:
DQ-BSA-Red is a bovine serum albumin labeled with a red fluorescent dye that can be used to detect lysosomal activity. The excitation wavelength and emission wavelength of DQ-BSA-Red are 590 nm and 620 nm; respectively. The BSA molecule in DQ-BSA-Red is labeled with high concentration of red fluorescent dye in multiple sites; which shows high fluorescence self-inhibition. Once DQ-BSA-RED enters the lysosome; DQ-BSA is cleaved by lysosomal proteases; resulting in unquenched and released fluorescent fragments; emitting bright fluorescence. Inactivated lysosomes are unable to degrade the BSA protein and thus have a lower or even no fluorescent signal[1].
Molecular Weight:
N/A
Purity:
0
References:
[1]Marwaha R, et al. DQ-Red BSA Trafficking Assay in Cultured Cells to Assess Cargo Delivery to Lysosomes. Bio Protoc. 2017 Oct 5;7(19):e2571.
Research Area:
Others
Shipping Conditions:
Dry Ice
Storage Conditions:
-80[o]C; protect from light
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
Pathway:
Others
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