4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate (sodium)
Product Sizes
1 mg
£ POA
HY-D1633A-1MG
About this Product
- SKU:
- HY-D1633A
- CAS Number:
- 206443-06-3
- Extra Details:
- 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside; which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds; electrostatic interactions; and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A)[1][2].
- Molecular Weight:
- 440.35
- Purity:
- 99.92
- References:
- [1]van Diggelen OP, et al. A fluorimetric enzyme assay for the diagnosis of Morquio disease type A (MPS IV A). Clin Chim Acta. 1990 Feb 28;187(2):131-9.|[2]Olarte-Avellaneda S, et al. Computational analysis of human N-acetylgalactosamine-6-sulfate sulfatase enzyme: an update in genotype-phenotype correlation for Morquio A. Mol Biol Rep. 2014 Nov;41(11):7073-88.
- Research Area:
- Others
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
- Pathway:
- Others
