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Proteins and Peptides

6-ROX

Product Sizes
10 mg
£ POA
HY-D0053-10MG
50 mg
£ POA
HY-D0053-50MG
100 mg
£ POA
HY-D0053-100MG
5 mg
£ POA
HY-D0053-5MG
10mM/1mL
£ POA
HY-D0053-10MM
25 mg
£ POA
HY-D0053-25MG
About this Product
SKU:
HY-D0053
Additional Names:
6-Carboxy-X-rhodamine
CAS Number:
194785-18-7
Extra Details:
6-ROX is a selective fluorescent probe and potential inhibitor of COX-2. 6-ROX binds to the active site of COX-2 and inhibits its conversion of arachidonic acid into prostaglandins. 6-ROX is often used in the field of optical imaging related to tumors and inflammation; and helps detect diseased tissues with high expression of COX-2[1][2].
Molecular Weight:
534.60
Purity:
98.43
References:
[1]Uddin MJ, et al. Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents. Bioconjug Chem. 2013 Apr 17;24 (4) :712-23.|[2]Butkevich AN, et al. Hydroxylated Fluorescent Dyes for Live-Cell Labeling: Synthesis, Spectra and Super-Resolution STED. Chemistry. 2017 Sep 7;23 (50) :12114-12119.
Research Area:
Others
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
Pathway:
Others
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