3;6-Diaminoacridine (dihydrochloride)
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HY-B1741A-1EACH
About this Product
- SKU:
- HY-B1741A
- Additional Names:
- 3,6-Diaminoacridine (dihydrochloride)
- CAS Number:
- 531-73-7
- Extra Details:
- Proflavine dihydrochloride is a multifunctional acridine compound. 3;6-Diaminoacridine dihydrochloride is an acridine dye and also a DNA inserter. Proflavine dihydrochloride is a potent broad-spectrum antibacterial agent; and its mechanism is to insert into bacterial DNA; interfering with replication and transcription; causing bacterial lysis. 3;6-Diaminoacridine dihydrochloride is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3;6-Diaminoacridine dihydrochloride can penetrate the stratum corneum of the skin and accumulate in the cell nucleus and long-term exposure may induce skin cancer or other malignant tumors[1][2][3].
- Molecular Weight:
- 282.17
- References:
- [1]Mansour K.Gatasheh, et al. Proflavine an acridine DNA intercalating agent and strong antimicrobial possessing potential properties of carcinogen. Karbala International Journal of Modern Science. 2017 Dec, 3(4): 272-278.|[2]Jiaxin Chen, et al. Determination of proflavine in rat whole blood without sample pretreatment by laser desorption postionization mass spectrometry. Anal Bioanal Chem. 2017 Apr;409(11):2813-2819.|[3]Mansour K.Gatasheh, et al. Proflavine an acridine DNA intercalating agent and strong antimicrobial possessing potential properties of carcinogen. Karbala International Journal of Modern Science. 2017 Dec, 3(4): 272-278.
- Research Area:
- Cancer; Infection; Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
