9-Aminoacridine
Product Sizes
250 mg
£ POA
HY-B1422-250MG
500 mg
£ POA
HY-B1422-500MG
1 g
£ POA
HY-B1422-1G
10mM/1mL
£ POA
HY-B1422-10MM
About this Product
- SKU:
- HY-B1422
- Additional Names:
- Aminacrine
- Application:
- Antibody Microarray
- CAS Number:
- 90-45-9
- Extra Details:
- 9-Aminoacridine; a fluorescent probe; acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections[1][2][3].
- Molecular Weight:
- 194.24
- Purity:
- 99.36
- References:
- [1]S Grzesiek, et al. The 'delta pH'-probe 9-aminoacridine: response time, binding behaviour and dimerization at the membrane. Biochim Biophys Acta. 1988 Mar 3;938(3):411-24.|[2]Pengfei She, et al. Repurposing 9-Aminoacridine as an Adjuvant Enhances the Antimicrobial Effects of Rifampin against Multidrug-Resistant Klebsiella pneumonia. Microbiol Spectr. 2023 Jun 15;11(3):e0447422.|[3]Irene Guendel, et al. 9-Aminoacridine inhibition of HIV-1 Tat dependent transcription. Virol J. 2009 Jul 24:6:114.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
- Pathway:
- Anti-infection
