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Proteins and Peptides

(S)-Hydroxychloroquine

Product Sizes
100 mg
£ POA
HY-B1370A-100MG
10 mg
£ POA
HY-B1370A-10MG
5 mg
£ POA
HY-B1370A-5MG
50 mg
£ POA
HY-B1370A-50MG
25 mg
£ POA
HY-B1370A-25MG
About this Product
SKU:
HY-B1370A
Additional Names:
(S)-HCQ
CAS Number:
137433-24-0
Extra Details:
(S)-Hydroxychloroquine ((S)-HCQ) is the enantiomer of Hydroxychloroquine[1]. Hydroxychloroquine; a synthetic antimalarial agent; inhibits Toll-like receptor 7/9 (TLR7/9) signaling; and shows efficiently inhibits SARS-CoV-2 infection in vitro[2][3][4].
Molecular Weight:
335.87
References:
[1]Cardoso CD, et al. Enantioselective analysis of the metabolites of hydroxychloroquine and application to an in vitro metabolic study. J Pharm Biomed Anal. 2005 Apr 1;37(4):703-8.|[2]Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6.|[3]Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40.|[4]Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Mar 9. pii: ciaa237.
Research Area:
Infection
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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