Ipratropium (bromide hydrate) (Standard)
Product Sizes
50 mg
£ POA
HY-B1332R-50MG
25 mg
£ POA
HY-B1332R-25MG
100 mg
£ POA
HY-B1332R-100MG
10 mg
£ POA
HY-B1332R-10MG
About this Product
- SKU:
- HY-B1332R
- Additional Names:
- Sch 1000 (bromide hydrate) (Standard)
- CAS Number:
- 66985-17-9
- Extra Details:
- Ipratropium (bromide hydrate) (Standard) is the analytical standard of Ipratropium (bromide hydrate). This product is intended for research and analytical applications. Ipratropium bromide (Sch 1000) hydrate is a muscarinic receptor antagonist; with IC50s of 2.9 nM; 2 nM; and 1.7 nM for M1; M2; and M3 receptors; respectively. Ipratropium bromide hydrate relaxes smooth muscle; can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma[1][2][3][4][5].
- Molecular Weight:
- 430.38
- References:
- [1]Fryer AD, et al. Maclagan, Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur J Pharmacol, 1987. 139(2): p. 187-91. |[2]Harvey, et al. Maddock, Ipratropium Bromide-Mediated Myocardial Injury in In Vitro Models of Myocardial Ischaemia/Reperfusion. Toxicol Sci, 2014. |[3]Maria Prat, et al. Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl amides as potent and long acting muscarinic antagonists. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1736-1741. |[4]Wenhui Zhang, et al. Anti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats. Eur J Pharmacol. 2010 Feb 25;628(1-3):171-8. |[5]Venkatasamy R, et al. Novel relaxant effects of RPL554 on guinea pig tracheal smooth muscle contractility. Br J Pharmacol. 2016 Aug;173(15):2335-51.
- Research Area:
- Inflammation/Immunology; Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
