Meglutol
Product Sizes
100 mg
£ POA
HY-B1189-100MG
50 mg
£ POA
HY-B1189-50MG
10mM/1mL
£ POA
HY-B1189-10MM
About this Product
- SKU:
- HY-B1189
- Additional Names:
- Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid
- CAS Number:
- 503-49-1
- Extra Details:
- Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol; triglycerides; serum β-lipoprotein; and phospholipids; and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases[1][2].
- Molecular Weight:
- 162.14
- Purity:
- 99.95
- References:
- [1]Leipnitz G, et al. Evidence that 3‐hydroxy‐3‐methylglutaric acid promotes lipid and protein oxidative damage and reduces the nonenzymatic antioxidant defenses in rat cerebral cortex[J]. Journal of neuroscience research, 2008, 86(3): 683-693.
- Research Area:
- Metabolic Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Autophagy;Metabolic Enzyme/Protease
