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Proteins and Peptides

Pimethixene

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HY-B1101-1EACH
About this Product
SKU:
HY-B1101
Additional Names:
Pimetixene
Application:
Electron Microscopy
CAS Number:
314-03-4
Extra Details:
Pimethixene is antihistamine and antiserotonergic compound; acts as an antimigraine agent. Pimethixene is a highly potent antagonist of 5-HT1A; 5-HT2A; 5-HT2B; 5-HT2C; histamine H1; dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors; with pKis of 7.63; 10.22; 10.44; 8.42; 10.14; 8.19; 7.54; 8.61 and 9.38; respectively[1].
Molecular Weight:
293.43
References:
[1]Schmitz B, et al. BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs. Eur J Pharmacol. 2015 Mar 15;751:73-80.
Research Area:
Neurological Disease; Endocrinology
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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