Acenocoumarol
Product Sizes
5 mg
£ POA
HY-B1014-5MG
10 mg
£ POA
HY-B1014-10MG
50 mg
£ POA
HY-B1014-50MG
25 mg
£ POA
HY-B1014-25MG
10mM/1mL
£ POA
HY-B1014-10MM
About this Product
- SKU:
- HY-B1014
- CAS Number:
- 152-72-7
- Extra Details:
- Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist. Acenocoumarol inhibits MAPK/ERK/JNK signaling pathway; reduces the nuclear translocation of NF-κB p65; activates Akt/GSK3β signaling pathway. Acenocoumarol induces apoptosis in cell A549; arrests cell cycle at S phase[1][2][3][4].
- Molecular Weight:
- 353.33
- Purity:
- 99.17
- References:
- [1]Han HJ, et al., Acenocoumarol Exerts Anti-Inflammatory Activity via the Suppression of NF-κB and MAPK Pathways in RAW 264.7 Cells. Molecules. 2023 Feb 22;28(5):2075.|[2]Han H, et al., Acenocoumarol, an Anticoagulant Drug, Prevents Melanogenesis in B16F10 Melanoma Cells. Pharmaceuticals (Basel). 2023 Apr 17;16(4):604.|[3]Warzecha Z, et al., Therapeutic Effect of Low Doses of Acenocoumarol in the Course of Ischemia/Reperfusion-Induced Acute Pancreatitis in Rats. Int. J. Mol. Sci.2017, 18, 882. Int J Mol Sci. 2019 Jun 24;20(12):3086.|[4]Maity S, et al. Exploring acenocoumarol and silodosin as allosteric EGFR inhibitors for the treatment of non-small cell lung cancer[J]. F1000Research, 2024, 13(1398): 1398.
- Research Area:
- Cancer; Inflammation/Immunology; Cardiovascular Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;MAPK/ERK Pathway;NF-κB;PI3K/Akt/mTOR;Stem Cell/Wnt;TGF-beta/Smad;Vitamin D Related/Nuclear Receptor
