AZ-5104
Product Sizes
100 mg
£ POA
HY-B0793-100MG
10 mg
£ POA
HY-B0793-10MG
50 mg
£ POA
HY-B0793-50MG
200 mg
£ POA
HY-B0793-200MG
5 mg
£ POA
HY-B0793-5MG
10mM/1mL
£ POA
HY-B0793-10MM
25 mg
£ POA
HY-B0793-25MG
About this Product
- SKU:
- HY-B0793
- CAS Number:
- 1421373-98-9
- Extra Details:
- AZ-5104 is an active; demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1; 6; 1; 25 and 7 nM for EGFRL858R/T790M; EGFRL858R; EGFRL861Q; EGFR and ErbB4; respectively.
- Molecular Weight:
- 485.58
- Purity:
- 99.91
- References:
- [1]Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
