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Proteins and Peptides

Zaltoprofen

Product Sizes
100 mg
£ POA
HY-B0619-100MG
10 mg
£ POA
HY-B0619-10MG
50 mg
£ POA
HY-B0619-50MG
5 mg
£ POA
HY-B0619-5MG
10mM/1mL
£ POA
HY-B0619-10MM
About this Product
SKU:
HY-B0619
Additional Names:
CN100
CAS Number:
74711-43-6
Extra Details:
Zaltoprofen (CN100); a non-steroidal anti-inflammatory drug (NSAID); is a preferential and orally active COX-2 inhibitor; with IC50s of 1.3 and 0.34 μM for COX-1 and COX-2; respectively. Zaltoprofen exhibits powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain[1][2][3].
Molecular Weight:
298.36
Purity:
99.28
References:
[1]Kawai S, et, al. Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells. Eur J Pharmacol. 1998 Apr 17;347(1):87-94.|[2]Hirate K, et, al. Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors. Neurosci Res. 2006 Apr;54(4):288-94.|[3]Kameyama T, et, al. Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid in rat and mouse. Arzneimittelforschung. 1987 Jan;37(1):19-26.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Immunology/Inflammation
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