(3S;5S)-Atorvastatin
Product Sizes
100 mg
£ POA
HY-B0589C-100MG
10 mg
£ POA
HY-B0589C-10MG
50 mg
£ POA
HY-B0589C-50MG
5 mg
£ POA
HY-B0589C-5MG
10mM/1mL
£ POA
HY-B0589C-10MM
25 mg
£ POA
HY-B0589C-25MG
About this Product
- SKU:
- HY-B0589C
- Application:
- Immunoprecipitation
- CAS Number:
- 501121-34-2
- Extra Details:
- (3S;5S)-Atorvastatin is a inactive enantiomer of Atorvastatin. (3S;5S)-Atorvastatin can activate pregnane X receptor (PXR). Atorvastatin is an orally active HMG-CoA reductase inhibitor; has the ability to effectively decrease blood lipids[1][2].
- Molecular Weight:
- 558.64
- Purity:
- 95.0
- References:
- [1]Thomas A Kocarek, et al. Regulation of CYP2B6 and CYP3A Expression by Hydroxymethylglutaryl Coenzyme A Inhibitors in Primary Cultured Human Hepatocytes. Drug Metab Dispos. 2002 Dec;30(12):1400-5.|[2]Martina Korhonova, et al. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes. PLoS One. 2015 Sep 14;10(9):e0137720.|[3]Elena G Shcherbakova , et al. High-Throughput Assay for Enantiomeric Excess Determination in 1,2- And 1,3-Diols and Direct Asymmetric Reaction Screening. Chemistry. 2017 Jul 26;23(42):10222-10229.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
