Hexamethonium (Bromide)
Product Sizes
1 g
£ POA
HY-B0569-1G
5 g
£ POA
HY-B0569-5G
500 mg
£ POA
HY-B0569-500MG
25 g
£ POA
HY-B0569-25G
100 g
£ POA
HY-B0569-100G
50 g
£ POA
HY-B0569-50G
10 g
£ POA
HY-B0569-10G
10mM/1mL
£ POA
HY-B0569-10MM
About this Product
- SKU:
- HY-B0569
- CAS Number:
- 55-97-0
- Extra Details:
- Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist; with mixed competitive and noncompetitive activity. Hexamethonium Bromide has anti-hypertensive activity. Hexamethonium Bromide attenuates sympathetic activity and blood pressure in spontaneously hypertensive animal models[1][2][3][4].
- Molecular Weight:
- 362.19
- Purity:
- 99.91
- References:
- [1]Damian J. Williams, et al. Mechanisms involved in nicotinic acetylcholine receptor-induced neurotransmitter release from sympathetic nerve terminals in the mouse vas deferens. PLoS One. 2011; 6(12): e29209.|[2]Roger L. Papke, et al. Activation and Inhibition of Mouse Muscle and Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes. J Pharmacol Exp Ther. 2010 May; 333(2): 501–518.|[3]Brian T Hawkins, et al. Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors. Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H212-9.|[4]Peng Li, et al. Hexamethonium attenuates sympathetic activity and blood pressure in spontaneously hypertensive rats. Mol Med Rep. 2015 Nov;12(5):7116-22.
- Research Area:
- Neurological Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Membrane Transporter/Ion Channel;Neuronal Signaling
