Flavoxate (hydrochloride)
Product Sizes
5 g
£ POA
HY-B0549A-5G
500 mg
£ POA
HY-B0549A-500MG
1 g
£ POA
HY-B0549A-1G
100 mg
£ POA
HY-B0549A-100MG
About this Product
- SKU:
- HY-B0549A
- Additional Names:
- Rec-7-0040; DW61
- CAS Number:
- 3717-88-2
- Extra Details:
- Flavoxate hydrochloride is an orally active L-type Ca2+ channel inhibitor and antispasmodic. Flavoxate hydrochloride inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba2+ currents; regulating the brainstem micturition center; and stimulating G protein-coupled receptors. Consequently; Flavoxate hydrochloride induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate hydrochloride effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate hydrochloride can be used in research on overactive bladder and related voiding dysfunctions[1][2][3].
- Molecular Weight:
- 427.92
- Purity:
- 99.70
- References:
- [1]Dansette, P.M., et al. HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins. Exp Toxicol Pathol, 2000. 52(2): p. 145-8.|[2]Kimura, Y., et al., Mechanisms of the suppression of the bladder activity by flavoxate. Int J Urol, 1996. 3(3): p. 218-27.|[3]Oka, M., et al., Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of the micturition reflex in rats. Brain Res, 1996. 727(1-2): p. 91-8.
- Research Area:
- Cancer;Cardiovascular Disease;Infection;Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
